Loening S, Hawtrey C, Bonney W, Narayana A, Culp D A
Prostate. 1980;1(3):279-86. doi: 10.1002/pros.2990010303.
Cryosurgical destruction of primary adenocarcinoma of the prostate was performed via perineal route in 215 patients during a 12-year period. The average age of the patients was 66 years. The stage of the disease varied from stage B to D. In 74% of the patients, no clinical evidence of tumor was found in the prostatic fossa following cryosurgery. Few patients needed transurethral surgery and none needed repeated transurethral resections for obstructive symptoms. This experience suggests that local destruction of prostatic carcinoma can be achieved with little morbidity and mortality. Herein wer discuss the method of cryosurgery, stage and histology or tumor, survival, local recurrence, and complications.
在12年期间，对215例患者经会阴途径进行了前列腺原发性腺癌的冷冻手术破坏。患者的平均年龄为66岁。疾病分期从B期到D期不等。74%的患者在冷冻手术后前列腺窝未发现肿瘤的临床证据。少数患者需要经尿道手术，无一例因梗阻症状需要重复经尿道切除术。这一经验表明，前列腺癌的局部破坏可以在低发病率和死亡率的情况下实现。本文讨论了冷冻手术的方法、肿瘤的分期和组织学、生存率、局部复发及并发症。
