DeVoogd T, Nottebohm F
Science. 1981 Oct 9;214(4517):202-4. doi: 10.1126/science.7280692.
Ovariectomized adult female canaries were treated with physiological doses of testosterone, dihydrotestosterone, or estradiol. Singing, which is typical of males, occurred in the testosterone-treated birds but not in any of the other birds. The effect of these hormones was assessed on dendrites from a class of neurons in the nucleus robustus archistriatalis (RA), a forebrain nucleus for song control. The RA neurons of the testosterone-treated birds had dendritic trees resembling those of intact males. The RA neurons of the estradiol- and dihydrotesterone-treated birds resembled those of intact females. All hormone-treated groups had dendrites that were significantly longer than those of untreated ovariectomized females. Thus gonadal hormones induce dendritic growth in the adult avian brain.
对成年雌性金丝雀进行卵巢切除后，用生理剂量的睾酮、双氢睾酮或雌二醇进行处理。雄性特有的鸣叫出现在接受睾酮处理的鸟类中，而其他鸟类均未出现。对用于控制鸣叫的前脑核团——古纹状体粗核（RA）中的一类神经元的树突，评估了这些激素的作用。接受睾酮处理的鸟类的RA神经元具有类似于完整雄性的树突树。接受雌二醇和双氢睾酮处理的鸟类的RA神经元类似于完整雌性的神经元。所有接受激素处理的组的树突都明显长于未处理的卵巢切除雌性的树突。因此，性腺激素可诱导成年鸟类大脑中的树突生长。
