Rat liver aldehyde dehydrogenase--immunochemical identity of 2,3,7,8-tetrachlorodibenzo-p-dioxin inducible normal liver and 2-acetylaminofluorene inducible hepatoma isozymes. - Suppr | 超能文献

Rat liver aldehyde dehydrogenase--immunochemical identity of 2,3,7,8-tetrachlorodibenzo-p-dioxin inducible normal liver and 2-acetylaminofluorene inducible hepatoma isozymes.

作者信息

Lindahl R, Roper M, Deitrich R A

出版信息

Biochem Pharmacol. 1978;27(20):2463-5. doi: 10.1016/0006-2952(78)90362-3.

DOI:10.1016/0006-2952(78)90362-3

Abstract

摘要

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Inducible (class 3) aldehyde dehydrogenase from rat hepatocellular carcinoma and 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated liver: distant relationship to the class 1 and 2 enzymes from mammalian liver cytosol/mitochondria.

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Increase of hepatic and serum aldehyde dehydrogenase activity after TCDD treatment.经2,3,7,8-四氯二苯并对二恶英（TCDD）处理后肝脏和血清醛脱氢酶活性增加。

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Differential gene expression in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Noncoordinate regulation of a TCDD-induced aldehyde dehydrogenase and cytochrome P-450c in the rat.对2,3,7,8-四氯二苯并对二恶英（TCDD）的差异基因表达。大鼠中TCDD诱导的醛脱氢酶和细胞色素P-450c的非协同调节。

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Induction of aldehyde dehydrogenases during hepatocarcinogenesis.肝癌发生过程中醛脱氢酶的诱导作用。

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2,3,7,8-Tetrachlorodibenzo-p-dioxin induction of aryl hydrocarbon hydroxylase in female rat liver. Evidence for de novo synthesis of cytochrome P-448.2,3,7,8-四氯二苯并-对-二恶英诱导雌性大鼠肝脏芳烃羟化酶。细胞色素P-448从头合成的证据。

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Aldehyde dehydrogenase in 2-acetylaminofluorene-induced rat hepatomas. Characterization of antigens recognized by anti-hepatoma aldehyde dehydrogenase sera.2-乙酰氨基芴诱导的大鼠肝癌中的醛脱氢酶。抗肝癌醛脱氢酶血清识别的抗原特性。

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Cloning and complete nucleotide sequence of a full-length cDNA encoding a catalytically functional tumor-associated aldehyde dehydrogenase.编码具有催化功能的肿瘤相关醛脱氢酶的全长cDNA的克隆及完整核苷酸序列

Proc Natl Acad Sci U S A. 1988 Mar;85(6):1782-6. doi: 10.1073/pnas.85.6.1782.

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Subcellular distribution and properties of aldehyde dehydrogenase from 2-acetylaminofluorene-induced rat hepatomas.2-乙酰氨基芴诱导的大鼠肝癌中醛脱氢酶的亚细胞分布及性质

Biochem J. 1979 Oct 1;183(1):55-64. doi: 10.1042/bj1830055.

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Multiple forms of inducible drug-metabolizing enzymes: a reasonable mechanism by which any organism can cope with adversity.多种形式的诱导性药物代谢酶：一种任何生物体都能应对逆境的合理机制。

Mol Cell Biochem. 1979 Sep 28;27(1):27-46. doi: 10.1007/BF00849277.