Bedarida G, D'Agostino F, Lavezzi C, Tamagni F
Boll Ist Sieroter Milan. 1978 May 31;57(2):160-4.
The Authors consider the different opinions expressed about the HBsAg screening in blood donors and its usefulness in preventing post transfusional hepatitis B (PTHB). They report data on the incidence of such a disease, as observed in their transfusional experience during the last 5 years, with a comparison between results obtained after CEP and RIA screening systems. The Authors point out the results of their retrospective investigation: the transfusion blood with a low HBsAg titre showed to be more infectious than the blood with high titre. Consequently, it is necessary to use more sensitive methods for HBsAg screening and possibly to increase their sensitivity or to combine them with other methods fit to evidence further markers of virus B.
作者们探讨了关于献血者乙肝表面抗原（HBsAg）筛查及其在预防输血后乙型肝炎（PTHB）方面作用的不同观点。他们报告了在过去5年输血实践中观察到的该疾病发病率数据，并对比了酶免疫分析（CEP）和放射免疫分析（RIA）筛查系统的结果。作者们指出了他们回顾性调查的结果：低HBsAg滴度的输血用血比高滴度的更具传染性。因此，有必要采用更敏感的方法进行HBsAg筛查，可能需要提高其敏感性，或者将其与其他适合检测乙肝病毒更多标志物的方法相结合。
