Vox Sang. 1977;32(6):346-63.
Third generation donor screening for hepatitis B is not generally efficacious in reducing PTH B except under certain epidemiological conditions. The nature of the remaining cases of PTH varies from region to region and depends on actual epidemiological circumstances. Cases of HB, transmitted by HBsAg-negative but nevertheless HBV-infectious blood, should be considered as well as cases of HB, transmitted by vehicles other than transfusion-blood, but confusingly also classified as PTH. Hepatitis A and hepatitis due to agents not yet identified occurring in blood recipients need further investigation. In such cases it remains an open question too, whether the disease is mainly transmitted with the transfusion-blood or by other vehicles, associated with large and long-lasting wounds or hospital environments as closely as blood transfusions are.
第三代乙肝供血者筛查一般在降低输血后乙肝(PTH B)方面效果不佳,除非在特定的流行病学条件下。输血后乙肝剩余病例的性质因地区而异,取决于实际的流行病学情况。应考虑由乙肝表面抗原(HBsAg)阴性但仍具传染性的血液传播的乙肝病例,以及由输血以外的媒介传播但也令人困惑地归类为输血后乙肝的乙肝病例。输血受者中发生的甲型肝炎以及由尚未明确的病原体引起的肝炎需要进一步调查。在这些情况下,疾病主要是通过输血传播还是通过其他媒介传播,是否像输血一样与大面积、长期伤口或医院环境密切相关,仍是一个悬而未决的问题。