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男性生育力研究中的人类精液天冬氨酸氨基转移酶和丙氨酸氨基转移酶活性

Human semen aspartate aminotransferase and alanine aminotransferase activity in male fertility studies.

作者信息

Buitrago J M, Diez L C, Battaner E

出版信息

Andrologia. 1981 Jul-Aug;13(4):335-41. doi: 10.1111/j.1439-0272.1981.tb00058.x.

DOI:10.1111/j.1439-0272.1981.tb00058.x
PMID:7283187
Abstract

The enzymatic activities of aminotransferases AST and ALT have been measured in the semen of a group of 98 subjects undergoing fertility studies, correlated with spermatic density and motility. An AST/ALT ratio was obtained for all patients. The results indicate that there exists a correlation between both enzymes' activities and spermatic density and motility. In two cases of excretory azoospermia, an elevated AST/ALT relation was obtained, while in two cases f secretory azoospermia a low AST/ALT ratio was seen. Aminotransferase values can thus be considered a useful piece of data in the evaluation of seminal quality, and the AST/ALT ratio used more specifically in te discrimination of the various types of azoospermia.

摘要

在一组98名接受生育能力研究的受试者的精液中,检测了转氨酶AST和ALT的酶活性,并将其与精子密度和活力进行了关联。计算了所有患者的AST/ALT比值。结果表明,这两种酶的活性与精子密度和活力之间存在相关性。在两例排泄性无精子症患者中,AST/ALT比值升高,而在两例分泌性无精子症患者中,AST/ALT比值较低。因此,转氨酶值可被视为评估精液质量的有用数据,而AST/ALT比值更具体地用于区分各种类型的无精子症。

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