González Buitrago J M, García Diez L C, Meza S, Juanes M
Med Clin (Barc). 1981 May 10;76(9):401-4.
The enzymatic activity of gammaglutamyl-transferase was measured in the semen of 79 male subjects undertaking fertility studies. The mean value obtained at 30 degrees C was 4898 +/- 2185 (mean +/- SD), which is 250 times the normal mean value in serum measured under identical conditions. No significant correlation was found between gammaglutamyl-transferase activity and sperm density, active lineal motility, and number with normal motility. Nor was a correlation found between gammaglutamyl-transferase activity and the concentration of citric acid, a marker of prostatic function, or fructose, a marker of seminal vesicle function. Very high levels of gammaglutamyl-transferase (25,000 and 16,850 U/l), and of citric acid (4,000 and 3,500 mg/dl) were found in two cases of excretory azoospermia, indicating that the prostate is probably the main origin of the enzyme, as described by other authors. Therefore, gammaglutamyl-transferase enzymatic activity could be utilized as a parameter of prostatic function in studies of male fertility.
在79名接受生育力研究的男性受试者的精液中检测了γ-谷氨酰转移酶的酶活性。在30摄氏度下获得的平均值为4898±2185（平均值±标准差），这是在相同条件下血清正常平均值的250倍。未发现γ-谷氨酰转移酶活性与精子密度、直线活动率以及具有正常活动能力的精子数量之间存在显著相关性。γ-谷氨酰转移酶活性与前列腺功能标志物柠檬酸或精囊功能标志物果糖的浓度之间也未发现相关性。在两例排泄性无精子症病例中发现γ-谷氨酰转移酶（分别为25000和16850 U/l）以及柠檬酸（分别为4000和3500 mg/dl）水平非常高，这表明正如其他作者所描述的，前列腺可能是该酶的主要来源。因此，在男性生育力研究中，γ-谷氨酰转移酶的酶活性可作为前列腺功能的一个参数。
