Tsien R Y
Biophys J. 1978 Nov;24(2):561-7. doi: 10.1016/S0006-3495(78)85402-2.
Recent experiments (1,2) have shown that hydrophobic ions adsorbed to lipid membranes repel each other significantly at densities as low as one charge every few tens of square nanometers. This paper shows how to calculate the mutual repulsion of a population of such ions, assumed to be discrete but free to diffuse laterally in the plane of the membrane. The results fall between those for uniformly smeared charges (the "three-capacitor" model) and those for discrete charges immobilized on a periodic lattice.
最近的实验(1,2)表明,吸附在脂质膜上的疏水离子在密度低至每几十平方纳米一个电荷时就会相互显著排斥。本文展示了如何计算这类离子群体的相互排斥力,假设这些离子是离散的,但可在膜平面内自由横向扩散。结果介于均匀涂抹电荷(“三电容”模型)和固定在周期性晶格上的离散电荷的结果之间。