Janghorbani M, Young V R, Gramlich J W, Machlan L A
Clin Chim Acta. 1981 Aug 10;114(2-3):163-71. doi: 10.1016/0009-8981(81)90389-2.
Radiochemical neutron activation analysis (RNAA) is compared with isotope ratio mass spectrometry (IRMS) for the measurement of 70Zn isotopic enrichment in human plasma following oral administration of the isotope. It is shown that both techniques are suitable for this purpose, although IRMS yields more precise data. Each method, with its advantages and limitations, can be realistically employed to study kinetics of appearance of 70Zn in plasma obtained during human metabolic studies.
将放射化学中子活化分析(RNAA)与同位素比率质谱法(IRMS)进行比较,以测量口服该同位素后人血浆中(^{70}Zn)同位素的富集情况。结果表明,尽管IRMS能产生更精确的数据,但这两种技术都适用于此目的。每种方法都有其优缺点,在人体代谢研究中获得的血浆中(^{70}Zn)出现的动力学研究中都可以实际应用。