Bolonova L N, Iulish N R
Farmakol Toksikol. 1981 Jul-Aug;44(4):470-3.
A Soviet low-molecular weight polymeric preparation polyvinylpyridine-N-oxide in doses producing a marked antisilicotic effect (1 g/kg bw, 5 injections for 2 weeks or inhalations at a concentration of 57.9 +/- 4.11 mg/m3 for one hour a day 5 times a week over 8 months or throughout the entire pregnancy) does not affect generative function of rats or mice and progeny of two generations.
一种苏联的低分子量聚合物制剂聚乙烯吡啶-N-氧化物,在产生显著抗矽肺作用的剂量下(1克/千克体重,2周内注射5次,或在8个月内每周5天、每天1小时以57.9±4.11毫克/立方米的浓度吸入,或在整个孕期内如此),不会影响大鼠或小鼠的生殖功能以及两代后代。