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银屑病的光化学疗法。清除及长期维持治疗的临床研究。

Photochemotherapy of psoriasis. Clinical study of clearing and long-term maintenance treatment.

作者信息

Burger P M, Tijssen J G, Suurmond D

出版信息

Dermatologica. 1981;163(3):213-28.

PMID:7286361
Abstract

PUVA therapy was administered to 140 patients with psoriasis. The results of clearing and long-term maintenance treatment are reported. Clearing requirements were in general similar to those reported by Melski and co-workers. The skin of a majority of the patients (79%) could be kept in a good condition by a maintenance-treatment schedule of once every 2 weeks or less. This result is better than the results reported by other authors. Extra topical treatment for residual lesions during maintenance consisted of small amounts of corticosteroids. The maximum length of the treatment intervals during maintenance showed definite individual variations. Patients who required one treatment a week or more to keep the skin cleared were dropped from the study.

摘要

对140例银屑病患者进行了补骨脂素加长波紫外线(PUVA)治疗。报告了清除效果和长期维持治疗的结果。清除要求总体上与梅尔斯基及其同事报告的相似。大多数患者(79%)的皮肤通过每2周或更短时间一次的维持治疗方案可保持良好状态。这一结果优于其他作者报告的结果。维持治疗期间对残留皮损的额外局部治疗包括少量皮质类固醇。维持治疗期间治疗间隔的最长时长存在明显个体差异。每周需要接受一次或更多次治疗以保持皮肤清除的患者被排除在研究之外。

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