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银屑病的光化学疗法。清除及长期维持治疗的临床研究。

Photochemotherapy of psoriasis. Clinical study of clearing and long-term maintenance treatment.

作者信息

Burger P M, Tijssen J G, Suurmond D

出版信息

Dermatologica. 1981;163(3):213-28.

PMID:7286361
Abstract

PUVA therapy was administered to 140 patients with psoriasis. The results of clearing and long-term maintenance treatment are reported. Clearing requirements were in general similar to those reported by Melski and co-workers. The skin of a majority of the patients (79%) could be kept in a good condition by a maintenance-treatment schedule of once every 2 weeks or less. This result is better than the results reported by other authors. Extra topical treatment for residual lesions during maintenance consisted of small amounts of corticosteroids. The maximum length of the treatment intervals during maintenance showed definite individual variations. Patients who required one treatment a week or more to keep the skin cleared were dropped from the study.

摘要

对140例银屑病患者进行了补骨脂素加长波紫外线(PUVA)治疗。报告了清除效果和长期维持治疗的结果。清除要求总体上与梅尔斯基及其同事报告的相似。大多数患者(79%)的皮肤通过每2周或更短时间一次的维持治疗方案可保持良好状态。这一结果优于其他作者报告的结果。维持治疗期间对残留皮损的额外局部治疗包括少量皮质类固醇。维持治疗期间治疗间隔的最长时长存在明显个体差异。每周需要接受一次或更多次治疗以保持皮肤清除的患者被排除在研究之外。

相似文献

1
Photochemotherapy of psoriasis. Clinical study of clearing and long-term maintenance treatment.银屑病的光化学疗法。清除及长期维持治疗的临床研究。
Dermatologica. 1981;163(3):213-28.
2
Comparison of phototherapy (UV-B) and photochemotherapy (PUVA) for clearing and maintenance therapy of psoriasis.光疗(UV-B)与光化学疗法(PUVA)治疗银屑病清除期及维持期的疗效比较
Arch Dermatol. 1984 Jan;120(1):52-7.
3
Psoralens and UV-A and UV-B twice weekly for the treatment of psoriasis.补骨脂素与紫外线A及紫外线B每周两次用于治疗银屑病。
Arch Dermatol. 1984 Sep;120(9):1169-73.
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Long-term safety of trioxsalen bath PUVA treatment: an 8-year follow-up of 149 psoriasis patients.补骨脂素浴联合光化学疗法(PUVA)治疗的长期安全性:149例银屑病患者的8年随访
Photodermatol. 1984 Feb;1(1):18-22.
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[Combined oral retinoid and PUVA therapy in the treatment of psoriasis and psoriatic arthropathy (author's transl)].联合口服维甲酸与补骨脂素紫外线A光化学疗法治疗银屑病和银屑病关节炎(作者译)
Ann Dermatol Venereol. 1981;108(2):131-7.
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Are topical corticosteroids useful adjunctive therapy for the treatment of psoriasis with ultraviolet radiation? A review of the literature.外用皮质类固醇激素作为紫外线治疗银屑病的辅助疗法是否有用?文献综述。
Arch Dermatol. 1991 Nov;127(11):1708-13.
7
Long-term photochemotherapy for psoriasis: a histopathological and clinical follow-up study with special emphasis on tumour incidence and behavior of pigmented lesions.银屑病的长期光化学疗法:一项组织病理学和临床随访研究,特别关注肿瘤发生率和色素沉着性病变的表现。
Acta Derm Venereol. 1983;63(3):215-21.
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Treatment of palmoplantar psoriasis with topical methoxsalen plus long-wave ultraviolet light.外用甲氧沙林加长波紫外线治疗掌跖银屑病。
Arch Dermatol. 1980 Nov;116(11):1257-61.
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[Oral photochemotherapy (author's transl)].[口服光化学疗法(作者译)]
Wien Klin Wochenschr Suppl. 1977;75:1-30.
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The importance of patient selection for photochemotherapy in psoriasis.银屑病光化学疗法中患者选择的重要性。
Can Med Assoc J. 1981 Apr 15;124(8):1016-8.

引用本文的文献

1
PUVA bath therapy strongly suppresses immunological and epidermal activation in psoriasis: a possible cellular basis for remittive therapy.补骨脂素加紫外线A光浴疗法强烈抑制银屑病中的免疫和表皮激活:缓解疗法的一种可能细胞基础。
J Exp Med. 1994 Jul 1;180(1):283-96. doi: 10.1084/jem.180.1.283.