甘油对热诱导细胞毒性的保护作用。
Protection of heat induced cytoxicity by glycerol.
作者信息
Lin P S, Kwock L, Hefter K
出版信息
J Cell Physiol. 1981 Sep;108(3):439-43. doi: 10.1002/jcp.1041080318.
Glycerol, at concentrations of 2-10% is a potent hyperthermic (43 degrees - 45 degrees C)protector of cultured Chinese hamster cells, V79. Furthermore, the sensitization effect of low pH on heat death is also drastically reduced by the addition of glycerol into the culture medium. Together with the known cellular effects of heat and the role of glycerol in various cellular structures and functions, the data suggest that microtubules and membranes may be involved in the expression of heat-induced cell death.
浓度为2% - 10%的甘油是培养的中国仓鼠V79细胞的一种有效的高温（43摄氏度 - 45摄氏度）保护剂。此外，通过向培养基中添加甘油，低pH对热死亡的致敏作用也会大幅降低。结合已知的热对细胞的影响以及甘油在各种细胞结构和功能中的作用，这些数据表明微管和细胞膜可能参与了热诱导细胞死亡的表达。
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