Fernández Sánchez B, Rodrigo Angulo M, Cano García J, Rodriguez Echandía E L
Cell Tissue Res. 1978 Oct 30;193(3):399-411. doi: 10.1007/BF00225338.
The regeneration of the vallate papilla in the rat was studied by both light and electron microscopy. The papillae were excised and regeneration was studied at time intervals of 3 to 45 days. It was found that the vallate papilla is capable of regeneration after both partial and total papillectomies. The regenerated papillae were asymmetrical in shape. Several invaginations, independent of one another, were the equivalent of the original sulcus. Regeneration of the gustatory system occurred at circumscribed portions of the associated Von Ebner glands. The amounts of newly formed taste buds were proportional to the amount of nerve fibers in the subepithelial plexus. The regenerated taste buds showed normal histochemical and fine-structural characteristics. The results support the contention of some degree of specificity concerning the epithelium where taste bud regeneration occurs.
通过光学显微镜和电子显微镜对大鼠轮廓乳头的再生进行了研究。切除乳头后，在3至45天的时间间隔内研究再生情况。结果发现，轮廓乳头在部分切除和全部切除后都能够再生。再生的乳头形状不对称。几个相互独立的内陷相当于原来的沟。味觉系统的再生发生在相关味腺的特定部位。新形成的味蕾数量与上皮下丛中神经纤维的数量成正比。再生的味蕾显示出正常的组织化学和精细结构特征。这些结果支持了关于味蕾再生发生的上皮具有一定程度特异性的观点。
