Alterations of plasma levels in malignant lymphoma.

Fibrinogen levels were investigated in the plasma of a group of patients with malignant lymphoma consisting of M. Hodgkin's and non-Hodgkin's lymphoma, and were found to be significantly higher in an acute onset of the disease and in relapses, than in a control group of healthy blood donors. In the terminal stages, fibrinogen levels in the plasma were observed to decline towards the upper normal limits. Plasma fibrinogen levels are considered to be a good indicator of the activity of the disease.