Catenazzo G, Torri A, Mantero M
Minerva Med. 1981 Sep 19;72(34):2283-8.
The results and validity of some of the latest and most significant epidemiological studies of the relation between risk factors and the clinical signs of arteriosclerosis are discussed, and the best rules for the prevention of arteriosclerotic vascular disease are suggested. Since primary prevention for the entire population is sound management, the practitioner should look for persons at risk, and initiate suitable hygienic, dietetic and, where necessary, pharmacological measures. This programme must not overlook secondary prevention, whose implementation demands the use of drugs (especially those that prevent the clumping of platelets). Under such conditions, ad is clear from the results of numerous multicentre studies, instigation of a multifactorial intervention has enabled the incidence of recurrences and mortality to be reduced.
讨论了一些关于危险因素与动脉硬化临床症状之间关系的最新且最重要的流行病学研究结果及其有效性，并提出了预防动脉硬化性血管疾病的最佳规则。由于对全体人群进行一级预防是合理的管理措施，从业者应寻找有风险的人群，并启动适当的卫生、饮食措施，必要时采取药物治疗措施。该方案绝不能忽视二级预防，二级预防的实施需要使用药物（尤其是那些防止血小板聚集的药物）。在这种情况下，从众多多中心研究的结果可以清楚地看出，开展多因素干预能够降低复发率和死亡率。
