Morini P L, Bianchi M A, Borsotti M
Minerva Med. 1981 Oct 20;72(40):2701-8.
The A. compare the values of serum ferritin and Desferrioxamine (DFO)-induced sideruria on 73 patients affected by different diseases. The results may be divided into three groups: a first one concerning patients with low serum ferritin and low DFO-induced sideruria, a second one of patients with normal serum ferritin and normal DFO-induced sideruria; in the third group of patients the A. found high values of serum ferritin and high or normal values of DFO-induced sideruria. The different behaviour observed in this III group of patients mostly affected by malignancy may be ascribed, in all those cases with high ferritin and normal sideruria, to a direct production of isoferritins by cancer cells.
A.比较了73例患有不同疾病的患者的血清铁蛋白值和去铁胺(DFO)诱导的尿铁。结果可分为三组:第一组是血清铁蛋白低且DFO诱导的尿铁低的患者;第二组是血清铁蛋白正常且DFO诱导的尿铁正常的患者;在第三组患者中,A.发现血清铁蛋白值高且DFO诱导的尿铁值高或正常。在这组主要受恶性肿瘤影响的第三组患者中观察到的不同表现,在所有铁蛋白高且尿铁正常的病例中,可能归因于癌细胞直接产生异铁蛋白。