Jensen J A, Festa E, Smith D S, Cayer M
Science. 1981 Oct 30;214(4520):566-9. doi: 10.1126/science.7291995.
The complement system of the nurse shark was investigated. Six functionally pure components were isolated from a single serum sample. Sequential reactions of the components with sensitized sheep erythrocytes resulted in membrane lesions indistinguishable from the "holes" caused by guinea pig complement.