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[辐照鲜鱼在慢性实验中的致突变特性]

[Mutagenic properties of irradiated fresh fish in a chronic experiment].

作者信息

Zaĭtsev A N, Osipova I N

出版信息

Vopr Pitan. 1981 Jul-Aug(4):53-6.

PMID:7293107
Abstract

The mutagenic action of fresh fish irradiated in a dose of 200 kGy was studied in chronic experiments on 5 generations of rats. The mutagenic activity was assessed from the induction of dominant lethal mutations in sex cells of males and from the formation of chromosome aberrations (bridges and fragments) in bone marrow. The results of calculating the mutagenicity rate and cytogenetic analysis indicated no mutagenic action of irradiated fresh fish on sex cells and bone marrow of rats given irradiated fish for a long period of time.

摘要

在对五代大鼠进行的慢性实验中,研究了剂量为200千戈瑞辐照的鲜鱼的诱变作用。通过诱导雄性生殖细胞中的显性致死突变以及骨髓中染色体畸变(桥和片段)的形成来评估诱变活性。诱变率计算结果和细胞遗传学分析表明,长时间给大鼠喂食辐照鲜鱼后,辐照鲜鱼对大鼠的生殖细胞和骨髓没有诱变作用。

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