Doering G, Doering F, Hänsgen K, Podhaisky H, Preuss E G, Seige K
Z Gesamte Inn Med. 1981 Aug 1;36(15):524-7.
In 34 male patients with peripheral arterial occlusive disease of the lower extremities the individual responsibility to an intraarterial adenosine triphosphate infusion was tested with the help of Doppler-sonographic poststenotic measurements of the systolic blood pressure as well as comparatively to this by determination of the arterial blood-flow in rest in the region of the calf. While the greater part of the patients with occlusive disease reacted with a significant increase of the blood supply, nearly with the same frequency a decrease of pressure or no change could be established concerning the behaviour of the peripheral pressure. For the judgment of the efficacy of an intraarterial infusion treatment in the acute experiment plethysmographic measurements of the blood-flow are, therefore, more suitable and should be preferred to Doppler-sonographic pressure parameters. As to the controls of long-term therapy under conservative treatment as well as for the judgment of the success in the reconstructive surgery of vessels, however, the post-stenotic measurements of the pressure stood the test apart from further methods in clinical practice.
在34例患有下肢周围动脉闭塞性疾病的男性患者中，借助多普勒超声对收缩期血压进行狭窄后测量，并通过测定小腿区域静息状态下的动脉血流，来检验个体对动脉内输注三磷酸腺苷的反应。虽然大部分闭塞性疾病患者的血供有显著增加，但就外周压力的变化而言，几乎以相同的频率出现压力降低或无变化的情况。因此，在急性实验中，对于判断动脉内输注治疗的疗效，血流容积描记测量更为合适，应优先于多普勒超声压力参数。然而，对于保守治疗下长期治疗的监测以及血管重建手术成功与否的判断，狭窄后压力测量在临床实践中除了其他方法外也经受住了考验。
