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接受注射用避孕药庚酸炔诺酮的女性排卵情况。

Occurrence of ovulation in women receiving the injectable contraceptive norethisterone oenanthate.

作者信息

Fotherby K, Howard G, Shrimanker K, Elder M, Bye P G

出版信息

Contraception. 1978 Nov;18(5):535-42. doi: 10.1016/0010-7824(78)90038-0.

Abstract

Ovarian function was studied in ten women receiving a single intramuscular injection of 200 mg norethisterone oenanthate. Two of the ten women appeared to ovulate within 60 days of injection and a further four within 90 days. Follicular activity probably not followed by ovulation occurred in five subjects within 60 days of the injection and in a further subject within 90 days. Only one subject showed no evidence of follicular or luteal activity during the course of this study. There was wide variation in the rate at which the administered gestagen was metabolised and no correlation between the rate of metabolism of norethisterone and the return of ovarian function or the ponderal index, height or weight of the subjects.

摘要

对10名单次肌内注射200mg庚酸炔诺酮的女性的卵巢功能进行了研究。10名女性中有2名在注射后60天内似乎排卵,另有4名在90天内排卵。5名受试者在注射后60天内出现卵泡活动但可能未排卵,另有1名受试者在90天内出现这种情况。在本研究过程中,只有1名受试者没有卵泡或黄体活动的迹象。所给予的孕激素代谢速率存在很大差异,炔诺酮的代谢速率与卵巢功能恢复或受试者的体重指数、身高或体重之间没有相关性。

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