Hedenstierna G, Järnberg P O, Gottlieb I
Anesthesiology. 1981 Oct;55(4):439-43. doi: 10.1097/00000542-198110000-00017.
A method based on body plethysmography for the assessment of thoracic gas volume (TGV) in the anesthetized, paralyzed subject is presented. The compression of thoracic gas following inflation is detected by measuring the difference between the inflation volume and the "box volume" change caused by the expansion of the chest. Model experiments showed good agreement between true and measured volumes with a residual standard deviation of 2 per cent. In studies on human subjects with healthy lungs during halothane anesthesia, the coefficient of variation of repeated measurements was 5 per cent. Comparative measurements with resting lung volume (FRC) determined by multiple breath nitrogen washout disclosed a larger volume by the box technique, a difference which was reduced but not eliminated by deep breathing during the nitrogen washout. This difference, amounting to 0.2 liters on the average, may be explained by abdominal gas and by the detection of trapped gas by the box technique but not by the nitrogen washout.
本文介绍了一种基于体容积描记法的方法，用于评估麻醉、麻痹状态下受试者的胸腔气体容积（TGV）。通过测量充气量与胸部扩张引起的“箱容积”变化之间的差异，检测充气后胸腔气体的压缩情况。模型实验表明，真实容积与测量容积之间具有良好的一致性，残余标准差为2%。在氟烷麻醉期间对健康肺部的人体受试者进行的研究中，重复测量的变异系数为5%。与通过多次呼吸氮洗脱法测定的静息肺容积（FRC）进行的对比测量显示，箱技术测量的容积更大，在氮洗脱期间进行深呼吸可使这种差异减小但未消除。这种平均为0.2升的差异可能是由腹部气体以及箱技术检测到的潴留气体导致的，而氮洗脱法未检测到。
