Frontera-Izquierdo P, Cabezuelo-Huerta G, Mulas F
An Esp Pediatr. 1981 Jun;14(6):411-5.
The fetal hydantoin syndrome is a variable pattern of altered growth (pre and postnatal), mental deficiency, unusual facies, distal phalangeal hypoplasia, and other defects occurring in some infants exposed in utero to hydantoins. This altered pattern of morphogenesis is distinct from other recognized disorders. It has been reported only in the offspring of women using hydantoins. One case is presented and several aspects of the diagnosis are discussed.
胎儿苯妥英综合征是一种在子宫内接触苯妥英类药物的婴儿中出现的生长改变(出生前后)、智力缺陷、特殊面容、远端指骨发育不全及其他缺陷的可变模式。这种形态发生的改变模式与其他已确认的疾病不同。仅在使用苯妥英类药物的女性后代中报道过。本文介绍了一例病例并讨论了诊断的几个方面。