胆固醇诱导动脉粥样硬化过程中主动脉糖胺聚糖的弹性蛋白酶抑制活性
Elastase-inhibitory activity of aortic glycosaminoglycans during cholesterol-induced atherosclerosis.
作者信息
Kar S, Saxena I D
出版信息
Ecotoxicol Environ Saf. 1978 Sep;2(2):129-32. doi: 10.1016/0147-6513(78)90003-9.
PMID:729515
Abstract
Elastase-inhibitory activity of aortic glycosaminoglycans, measured in vitro, was found to be significantly reduced in rabbits fed a 2% cholesterol diet for 60, 90, and 120 days. The reduction, suggested to be due to alteration in the composition of aortic glycosaminoglycans, may be relevant to the process of atherogenesis.
摘要
在体外测量时，发现喂食2%胆固醇饮食60天、90天和120天的兔子主动脉糖胺聚糖的弹性蛋白酶抑制活性显著降低。这种降低被认为是由于主动脉糖胺聚糖组成的改变，可能与动脉粥样硬化的发生过程有关。
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