Dosenko V Ie
O.O. Bogomolets National Medical University, Kyiv Ministry of Public Health of Ukraine.
Ukr Biokhim Zh (1978). 1998 Jul-Aug;70(4):88-94.
The role of the elastolytic system serum and arterial tissues in pathogenesis of vascular pathology was investigated on rabbits in experimental arterio-atherosclerosis. Activation of proteolytic enzymes, in particular elastase, sharp alteration capacity of inhibitors in arterial wall both at Menckeberg arteriosclerosis and atherosclerosis, permits to assume, that in the basis these different pathologic processes can lie general mechanisms, which will be realized through disturbance of the elastolytic system balance in blood vessels.
在实验性动脉粥样硬化的家兔身上，研究了弹性溶解系统血清和动脉组织在血管病变发病机制中的作用。在门克贝格动脉硬化和动脉粥样硬化过程中，蛋白水解酶尤其是弹性蛋白酶的激活，以及动脉壁中抑制剂能力的急剧改变，使我们可以推测，这些不同病理过程的基础可能存在共同机制，即通过血管中弹性溶解系统平衡的紊乱来实现。
