Bumsted R M, Ceilley R I, Panje W R, Crumley R L
Arch Otolaryngol. 1981 Nov;107(11):721-4. doi: 10.1001/archotol.1981.00790470069015.
A prospective study of 71 auricular malignant neoplasms was performed to identify lesions with a high risk of recurrence. Previously recommended margins for conventional surgical excision were marked. Then, all lesions were excised by the Mohs' technique. The Mohs' defect was compared with previously marked margins for conventional excision. Conventional excision would have been inadequate in 13% of primary and initially recurrent lesions smaller than 1 cm (clinical examination) and in 27% of primary lesions and 33% of recurrent lesions larger than 1 cm. All cases successfully excised by conventional excision would have resulted in a larger defect than the actual Mohs' defect. Morpheaform basal cell carcinoma was the most common lesion inadequately excised. Either cases of this histologic type or lesions larger than 1 cm or both require consideration for the use of the Mohs' technique.
对71例耳廓恶性肿瘤进行了一项前瞻性研究，以确定具有高复发风险的病变。标记了先前推荐的传统手术切除切缘。然后，所有病变均采用莫氏手术技术切除。将莫氏手术造成的缺损与先前标记的传统切除切缘进行比较。对于小于1厘米（临床检查）的原发性和初发性复发病变，13%采用传统切除切缘不足；对于大于1厘米的原发性病变，27%采用传统切除切缘不足；对于大于1厘米的复发性病变，33%采用传统切除切缘不足。所有通过传统切除成功切除的病例所造成的缺损都比实际的莫氏手术缺损大。硬斑病样基底细胞癌是最常出现切除不足的病变。这种组织学类型的病例、大于1厘米的病变或两者都需要考虑使用莫氏手术技术。
