Bailin P L, Levine H L, Wood B G, Tucker H M
Arch Otolaryngol. 1980 Nov;106(11):692-6. doi: 10.1001/archotol.1980.00790350034010.
Cutaneous carcinoma of the auricular and periauricular region can be diagnosed early and often cured; however, many of these tumors become difficult to treat because of local spread and regional metastasis. We have treated 122 patients with 145 cutaneous carcinomas of the auricular and periauricular region with either Mohs' histographic surgery or conventional excision with total microscopic marginal control. Inherent in these treatment modalities is the construction of detailed serial tissue maps for each tumor. From these maps, a three-dimensional composite for each tumor is derived, giving information about the direction of local spread of the tumors. The tumors have been found to extend locally through soft tissue into perichondrial, periosteal, and neurovascular planes, allowing for more distant occult spread. This knowledge of such patterns of tumor spread can be useful in planning treatment.
耳廓及耳周区域的皮肤癌能够早期诊断且通常可治愈；然而，这些肿瘤中的许多因局部扩散和区域转移而变得难以治疗。我们采用莫氏组织绘图手术或常规切除并进行全显微镜边缘控制的方法，治疗了122例患有145处耳廓及耳周区域皮肤癌的患者。这些治疗方式的内在要求是为每个肿瘤构建详细的连续组织图谱。从这些图谱中，可以得出每个肿瘤的三维合成图，从而提供有关肿瘤局部扩散方向的信息。已发现肿瘤可通过软组织局部延伸至软骨膜、骨膜和神经血管平面，从而导致更远距离的隐匿性扩散。了解这种肿瘤扩散模式有助于制定治疗方案。
