拉贝洛尔和普萘洛尔对女性性唤起时升压反应的影响。
The effect of labetalol and propranolol on the pressor response to sexual arousal in women.
作者信息
Riley A J, Riley E J
出版信息
Br J Clin Pharmacol. 1981 Sep;12(3):341-4. doi: 10.1111/j.1365-2125.1981.tb01223.x.
Abstract
1 The effect of a single oral dose of labetalol (100 mg), propranolol (80 mg) and placebo on the pressor response to sexual autostimulation has been studied in six female volunteers. 2 Labetalol but not propranolol significantly reduced the increase in blood pressure that occurred at orgasm. 3 The subjective features of the sexual response were assessed by each subject using visual analogue scales. 4 Subjects reported a significant reduction in vaginal lubrication with labetalol compared to both placebo and propranolol. 5 No other effects were noted.
摘要
- 研究了单次口服拉贝洛尔（100毫克）、普萘洛尔（80毫克）和安慰剂对6名女性志愿者性自慰刺激所致升压反应的影响。2. 拉贝洛尔可显著降低性高潮时出现的血压升高，而普萘洛尔则无此作用。3. 每位受试者使用视觉模拟量表评估性反应的主观特征。4. 与安慰剂和普萘洛尔相比，受试者报告服用拉贝洛尔后阴道润滑显著减少。5. 未观察到其他影响。
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本文引用的文献
1
Blood pressure and respiratory patterns during human coitus.人类性交过程中的血压和呼吸模式。
J Reprod Fertil. 1969 Aug;19(3):405-15. doi: 10.1530/jrf.0.0190405.
2
Reduction in the rise of systolic blood pressure during human coitus by the beta-adrenergic blocking agent, propranolol.β-肾上腺素能阻滞剂普萘洛尔降低人体性交时收缩压的升高幅度。
J Reprod Fertil. 1970 Aug;22(3):587-90. doi: 10.1530/jrf.0.0220587.
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Direct arterial pressure, heart rate and electrocardiogram during human coitus.人类性交过程中的直接动脉压、心率和心电图
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Modification of pressor responses induced by 'cold' [proceedings].“寒冷”引起的升压反应的改变[会议记录]
Br J Clin Pharmacol. 1977 Jun;4(3):389P.
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Psychosom Med. 1977 Mar-Apr;39(2):143-8. doi: 10.1097/00006842-197703000-00009.
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Haemodynamic effects of long-term oral labetalol.长期口服拉贝洛尔的血流动力学效应。
Br J Clin Pharmacol. 1976 Aug;3(4 Suppl 3):733-6.
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