• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Studies on the absorption of practically water-insoluble drugs following injection. IV. An approach for predicting relative intramuscular absorption rates of a drug in oily solution, aqueous suspension and aqueous surfactant solution in rats.

作者信息

Hirano K, Yamada H

出版信息

Chem Pharm Bull (Tokyo). 1981 May;29(5):1410-5. doi: 10.1248/cpb.29.1410.

DOI:10.1248/cpb.29.1410
PMID:7296708
Abstract
摘要

相似文献

1
Studies on the absorption of practically water-insoluble drugs following injection. IV. An approach for predicting relative intramuscular absorption rates of a drug in oily solution, aqueous suspension and aqueous surfactant solution in rats.注射后几乎不溶于水的药物的吸收研究。IV. 预测大鼠油性溶液、水混悬液和水性表面活性剂溶液中药物相对肌肉注射吸收速率的方法。
Chem Pharm Bull (Tokyo). 1981 May;29(5):1410-5. doi: 10.1248/cpb.29.1410.
2
Studies on the absorption of practically water-insoluble drugs following injection. III. Intramuscular absorption from aqueous nonionic surfactant solutions in rats.注射后几乎不溶于水的药物的吸收研究。III. 大鼠体内从非离子表面活性剂水溶液中的肌肉注射吸收情况
Chem Pharm Bull (Tokyo). 1981 Mar;29(3):834-43. doi: 10.1248/cpb.29.834.
3
Studies on the absorption of practically water-insoluble drugs following injection. II. Intramuscular absorption from aqueous suspensions in rats.注射后几乎不溶于水的药物的吸收研究。II. 大鼠体内水混悬液的肌肉注射吸收
Chem Pharm Bull (Tokyo). 1981 Mar;29(3):817-27. doi: 10.1248/cpb.29.817.
4
Studies on the absorption of practically water-insoluble drugs following injection. I. Intramuscular absorption from water-immiscible oil solutions in rats.注射后几乎不溶于水的药物的吸收研究。I. 大鼠体内从与水不混溶的油溶液中的肌肉注射吸收情况。
Chem Pharm Bull (Tokyo). 1981 Feb;29(2):519-31. doi: 10.1248/cpb.29.519.
5
Studies on the absorption of practically water-insoluble drugs following injection V: Subcutaneous absorption in rats from solutions in water immiscible oils.注射后几乎不溶于水的药物吸收的研究V：大鼠皮下从与水不混溶的油溶液中的吸收
J Pharm Sci. 1982 May;71(5):495-500. doi: 10.1002/jps.2600710505.
6
Simultaneous magnetic resonance imaging and pharmacokinetic analysis of intramuscular depots.肌肉内储库的磁共振成像与药代动力学分析的同步研究。
J Control Release. 2016 Apr 10;227:1-12. doi: 10.1016/j.jconrel.2016.02.029. Epub 2016 Feb 17.
7
Studies on the absorption of practically water-insoluble drugs following injection VI: Subcutaneous absorption from aqueous suspensions in rats.注射后几乎不溶于水的药物的吸收研究VI：大鼠皮下从水性混悬液中的吸收。
J Pharm Sci. 1982 May;71(5):500-5. doi: 10.1002/jps.2600710506.
8
Studies on the absorption of practically water-insoluble drugs following injection VIII: comparison of the subcutaneous absorption rates from aqueous suspensions in the mouse, rat, and rabbit.注射后几乎不溶于水的药物吸收研究VIII：小鼠、大鼠和兔皮下注射水性混悬液后的吸收速率比较
J Pharm Sci. 1983 Jun;72(6):608-12. doi: 10.1002/jps.2600720608.
9
Intramuscular absorption of drugs from oily solutions in the rat.大鼠体内油性溶液中药物的肌肉注射吸收情况。
Chem Pharm Bull (Tokyo). 1974 Jun;22(6):1275-84. doi: 10.1248/cpb.22.1275.
10
Studies on the absorption of practically water-insoluble drugs following injection VII: plasma concentration after different subcutaneous doses of a drug in aqueous suspension in rats.注射后几乎不溶于水的药物的吸收研究VII：大鼠皮下注射不同剂量药物水悬浮液后的血浆浓度
J Pharm Sci. 1983 Jun;72(6):602-7. doi: 10.1002/jps.2600720607.

引用本文的文献

1
Population Pharmacokinetics of Risperidone and Paliperidone in Schizophrenia: A Systematic Review.利培酮和帕利哌酮在精神分裂症中的群体药代动力学：一项系统评价。
Pharmaceuticals (Basel). 2025 May 8;18(5):698. doi: 10.3390/ph18050698.
2
Long-Acting Injectable Antipsychotics-A Review on Formulation and In Vitro Dissolution.长效注射用抗精神病药物——制剂与体外溶出度综述
Pharmaceutics. 2023 Dec 24;16(1):28. doi: 10.3390/pharmaceutics16010028.
3
Long-Acting Injectable Antipsychotics: A Systematic Review of Their Non-Systemic Adverse Effect Profile.
长效注射用抗精神病药物：对其非系统性不良反应特征的系统评价
Neuropsychiatr Dis Treat. 2021 Jun 14;17:1917-1926. doi: 10.2147/NDT.S309768. eCollection 2021.
4
Population Pharmacokinetics of a Novel Once-Every 3 Months Intramuscular Formulation of Paliperidone Palmitate in Patients with Schizophrenia.新型每三个月一次的棕榈酸帕利哌酮肌肉注射制剂在精神分裂症患者中的群体药代动力学
Clin Pharmacokinet. 2017 Apr;56(4):421-433. doi: 10.1007/s40262-016-0459-3.
5
The Pharmacokinetics of Second-Generation Long-Acting Injectable Antipsychotics: Limitations of Monograph Values.第二代长效注射用抗精神病药物的药代动力学：专论值的局限性。
CNS Drugs. 2015 Dec;29(12):975-83. doi: 10.1007/s40263-015-0295-2.
6
Population pharmacokinetics of intramuscular paliperidone palmitate in patients with schizophrenia: a novel once-monthly, long-acting formulation of an atypical antipsychotic.精神分裂症患者中肌肉注射棕榈酸帕利哌酮的群体药代动力学：一种新型的每月一次长效非典型抗精神病药物制剂
Clin Pharmacokinet. 2009;48(9):585-600. doi: 10.2165/11316870-000000000-00000.
7
Predictions of in vivo plasma concentrations from in vitro release kinetics: application to doxepin parenteral (i.m.) suspensions in lipophilic vehicles in dogs.根据体外释放动力学预测体内血浆浓度：在犬类亲脂性载体中多塞平注射用（肌肉注射）混悬液的应用。
Pharm Res. 1994 Jun;11(6):800-8. doi: 10.1023/a:1018913321164.
8
Testosterone in a cyclodextrin-containing formulation: behavioral and physiological effects of episode-like pulses in rats.含环糊精制剂中的睾酮：大鼠中类似发作性脉冲的行为和生理效应
Pharm Res. 1989 Jul;6(7):641-6. doi: 10.1023/a:1015922019038.