瑞典北部一个精神分裂症高发的隔离人群中的血浆多巴胺β-羟化酶活性

Plasma dopamine beta-hydroxylase activity in a North Swedish isolate with a high frequency of schizophrenia.

作者信息

Ross S B, Böök J A, Wetterberg L

出版信息

Clin Genet. 1981 May;19(5):415-7. doi: 10.1111/j.1399-0004.1981.tb00738.x.

DOI:10.1111/j.1399-0004.1981.tb00738.x

Abstract

Plasma dopamine beta-hydroxylase (DBH) activity was determined in 115 members of a North Swedish geographical isolate with a high frequency of schizophrenia, of which 30 persons had schizophrenia, and was compared with a Middle Swedish population of 185 apparently healthy persons. There was no significant difference between the schizophrenic group and their healthy relatives or between the North and Middle-Swedish populations. The number of persons with very low plasma DBH activity in the North Swedish population appeared to be less than those in the control population.

摘要

对瑞典北部一个精神分裂症高发的地理隔离人群中的115名成员测定了血浆多巴胺β-羟化酶（DBH）活性，其中30人患有精神分裂症，并与瑞典中部185名明显健康的人群进行了比较。精神分裂症患者组与其健康亲属之间以及瑞典北部和中部人群之间均无显著差异。瑞典北部人群中血浆DBH活性极低的人数似乎少于对照组人群。