Lopez-Novoa J M, Rengel M A, Hernando L
Experientia. 1978 Dec 15;34(12):1613-4. doi: 10.1007/BF02034707.
Bilateral adrenalectomy (ADX) or a sham procedure was performed in cirrhotic and control rats. After ADX, controls increased their sodium excretion with respect to the basal values but cirrhotics did not. When sodium-loaded, the ADX cirrhotic rats retained a significant amount of the load. These data do not support a primary role of aldosterone in the impaired sodium handling by cirrhotic rats.
对肝硬化大鼠和对照大鼠进行双侧肾上腺切除术（ADX）或假手术。ADX后，对照组相对于基础值增加了钠排泄，但肝硬化大鼠没有。当给予钠负荷时，ADX肝硬化大鼠保留了大量的负荷。这些数据不支持醛固酮在肝硬化大鼠钠处理受损中起主要作用。
