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The mechanism of trypsin catalysis at low pH. Proposal for a structural model.

作者信息

Antonini E, Ascenzi P

出版信息

J Biol Chem. 1981 Dec 10;256(23):12449-55.

PMID:7298667
Abstract
摘要

相似文献

1
The mechanism of trypsin catalysis at low pH. Proposal for a structural model.低pH条件下胰蛋白酶催化的机制。结构模型的提议。
J Biol Chem. 1981 Dec 10;256(23):12449-55.
2
Monoenzymatic model membranes: diffusion-reaction kinetics and phenomena.单酶模型膜：扩散-反应动力学与现象
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The effect of pre-incubation on trypsin kinetics at low pH.预孵育对低pH条件下胰蛋白酶动力学的影响。
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4
The hydrolysis of alpha-N-benzoyl-L-argininamide catalyzed by trypsin and acetyltrypsin. Dependence on pH.胰蛋白酶和乙酰胰蛋白酶催化的α-N-苯甲酰-L-精氨酸酰胺的水解。对pH的依赖性。
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pH dependence of tritium exchange with the C-2 protons of the histidines in bovine trypsin.氚与牛胰蛋白酶中组氨酸C-2质子交换的pH依赖性
Biochemistry. 1976 Aug 10;15(16):3458-64. doi: 10.1021/bi00661a010.
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Enzymatic activity at interfaces. I. Enzymatic activity of trypsin at the air-water interface.界面处的酶活性。I. 胰蛋白酶在气-水界面的酶活性。
Biochim Biophys Acta. 1974 Sep 11;364(1):146-58. doi: 10.1016/0005-2744(74)90142-9.
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Single peptide bond hydrolysis/resynthesis in squash inhibitors of serine proteinases. 1. Kinetics and thermodynamics of the interaction between squash inhibitors and bovine beta-trypsin.南瓜丝氨酸蛋白酶抑制剂中的单肽键水解/再合成。1. 南瓜抑制剂与牛β-胰蛋白酶相互作用的动力学和热力学
Biochemistry. 1994 Jan 11;33(1):200-7. doi: 10.1021/bi00167a026.
8
Steady-state and pre-steady-state kinetics of the trypsin-catalysed hydrolysis of alpha-CBZ-L-lysine-p-nitrophenyl ester.胰蛋白酶催化α-苄氧羰基-L-赖氨酸对硝基苯酯水解的稳态和前稳态动力学
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pH dependence of the equilibrium constant for the hydrolysis of the Arg 63 -Ile reactive-site peptide bond in soybean trypsin inhibitor (Kunitz).大豆胰蛋白酶抑制剂（Kunitz）中精氨酸63 - 异亮氨酸反应位点肽键水解平衡常数的pH依赖性
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Properties and specificity of the major anionic trypsin-like enzyme in the keratinolytic larvae of the webbing clothes moth.织网衣蛾角蛋白分解幼虫中主要阴离子类胰蛋白酶样酶的性质和特异性
Biochim Biophys Acta. 1975 May 23;391(1):201-11. doi: 10.1016/0005-2744(75)90167-9.

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Kinetic Studies of the Effect of pH on the Trypsin-Catalyzed Hydrolysis of -α-benzyloxycarbonyl-l-lysine--nitroanilide: Mechanism of Trypsin Catalysis.pH对胰蛋白酶催化水解α-苄氧羰基-L-赖氨酸-对硝基苯胺影响的动力学研究：胰蛋白酶催化机制
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Antibody-Mediated Catalysis in Infection and Immunity.
感染与免疫中的抗体介导催化作用
Infect Immun. 2017 Aug 18;85(9). doi: 10.1128/IAI.00202-17. Print 2017 Sep.
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Ligand binding to the FA3-FA4 cleft inhibits the esterase-like activity of human serum albumin.配体与FA3-FA4裂隙的结合会抑制人血清白蛋白的酯酶样活性。
PLoS One. 2015 Mar 19;10(3):e0120603. doi: 10.1371/journal.pone.0120603. eCollection 2015.
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Characterization of the prostate-specific antigen (PSA) catalytic mechanism: a pre-steady-state and steady-state study.前列腺特异性抗原（PSA）催化机制的表征：预稳态和稳态研究。
PLoS One. 2014 Jul 28;9(7):e102470. doi: 10.1371/journal.pone.0102470. eCollection 2014.
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Esterolytic Properties of Leucine-Proteinase, the Leucine-Specific Serine Proteinase from Spinach (Spinacia oleracea L.) Leaves : A Steady-State and Pre-Steady-State Study.叶菜类菠菜亮氨酸蛋白酶（亮氨酸特异性丝氨酸蛋白酶）的酯酶特性：稳态和预稳态研究。
Plant Physiol. 1986 Oct;82(2):591-3. doi: 10.1104/pp.82.2.591.
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Purification and Characterization of Leu-Proteinase, the Leucine Specific Serine Proteinase from Spinach (Spinacia oleracea L.) Leaves.菠菜（Spinacia oleracea L.）叶片中亮氨酸特异性丝氨酸蛋白酶——亮氨酸蛋白酶的纯化与特性分析
Plant Physiol. 1986 Jul;81(3):812-6. doi: 10.1104/pp.81.3.812.
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pH- and temperature-dependence of functional modulation in metalloproteinases. A comparison between neutrophil collagenase and gelatinases A and B.金属蛋白酶功能调节的pH值和温度依赖性。中性粒细胞胶原酶与明胶酶A和B的比较。
Biophys J. 2000 Oct;79(4):2138-49. doi: 10.1016/S0006-3495(00)76461-7.
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Catalytic and ligand binding properties of bovine trypsinogen and its complex with the effector dipeptide Ile-Val. A comparative study.牛胰蛋白酶原及其与效应二肽异亮氨酸-缬氨酸复合物的催化和配体结合特性。一项比较研究。
Mol Cell Biochem. 1984;60(2):163-81. doi: 10.1007/BF00222487.
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Catalytic properties of porcine pancreatic elastase: a steady-state and pre-steady-state study.猪胰弹性蛋白酶的催化特性：稳态和预稳态研究
Mol Cell Biochem. 1983;56(1):33-8. doi: 10.1007/BF00228766.