Minford A M, Hardy G J, Forsythe W I, Fitton J M, Rowe V L
J Bone Joint Surg Br. 1981;63B(4):597-600. doi: 10.1302/0301-620X.63B4.7298693.
A 13-year-old girl presented with a two-year history of pain in the right thigh and right forearm. Engelmann's disease was diagnosed on the basis of radiological appearances and histological examination of the bone. Her symptoms subsided after biopsy of the bone, but two weeks later she developed severe pain in the left tibia and was unable to walk. Radiological features of Engelmann's disease were found in the left tibia and other long bones although these bones had been radiologically normal one month previously. Treatment with prednisolone gave rapid relief of pain and allowed the patient to become mobile again. Four months later the radiological appearances showed significant improvement. The use of corticosteroids in this disorder is discussed.
一名13岁女孩有右大腿和右前臂疼痛两年的病史。根据骨骼的放射学表现和组织学检查诊断为恩格尔曼病。骨活检后她的症状有所缓解，但两周后她左胫骨出现剧痛，无法行走。尽管一个月前这些骨骼的放射学检查结果正常，但在左胫骨和其他长骨中发现了恩格尔曼病的放射学特征。泼尼松龙治疗使疼痛迅速缓解，患者又能够活动。四个月后放射学表现有显著改善。本文讨论了皮质类固醇在这种疾病中的应用。
