一种用于辅助微电极穿透小神经纤维的压电装置。
A piezoelectric device to aid penetration of small nerve fibers with microelectrodes.
作者信息
Hengstenberg R
出版信息
J Neurosci Methods. 1981 Oct;4(3):249-55. doi: 10.1016/0165-0270(81)90036-4.
A small piezoelectric device for cell penetration is described. It retracts the micropipette slowly by electrostriction, and pushes it very fast (less than 5 microsecond) forward by short-circuiting the transducer. The design, operation circuit, and performance under test conditions are described. Penetration examples from small nerve fibers (less than 5 micrometer) show that membrane puncture occurs only with the fast forward push. Cells are not noticeably damaged, even if the device is repeatedly operated after cell penetration.
描述了一种用于细胞穿透的小型压电装置。它通过电致伸缩缓慢缩回微量移液器，并通过使换能器短路将其非常快速地（小于5微秒）向前推。描述了该装置的设计、操作电路以及测试条件下的性能。从小神经纤维（小于5微米）进行穿透的示例表明，只有通过快速向前推才能发生膜穿刺。即使在细胞穿透后该装置重复操作，细胞也没有明显受损。
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