过氧-ATP类似物腺苷5'-过氧二磷酸的合成及生物活性
Synthesis and biological activity of the peroxy-ATP analogue, adenylyl 5'-peroxydiphosphate.
作者信息
Leonard N J, Rosendahl M S
出版信息
Nucleic Acids Symp Ser. 1981(9):141-4.
PMID:7301596
Abstract
An analogue of adenosine 5'-triphosphate, adenylyl 5'-peroxydiphosphate (beta, gamma-peroxy-ATP), in which a peroxide linkage replaces the terminal bridge oxygen of the triphosphate chain, has been synthesized. The chemical and biological properties of beta, gamma-peroxy-ATP in representative enzyme systems demonstrate its potential usefulness as a probe of enzymatic mechanism and structure.
摘要
腺苷5'-三磷酸的类似物腺苷酰5'-过氧二磷酸（β，γ-过氧-ATP）已被合成，其中过氧化物键取代了三磷酸链的末端桥氧。β，γ-过氧-ATP在代表性酶系统中的化学和生物学特性表明其作为酶促机制和结构探针的潜在用途。
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