Sposito M, Trollini O, Massi-Benedetti F
Pediatr Med Chir. 1981 Jan-Feb;3(1):33-6.
The level of glycosylated hemoglobin was determined in 39 diabetic children and in 94 normal children. In certain subjects, both diabetic and normal, the component HbA1c was also determined. After the evaluation of the results of their study, the Authors conclude that, for practical purposes, the determination of total glycosylated hemoglobin is sufficient and express doubt in the usefulness of this parameter for routine monitoring of metabolic balance in diabetic children. The Authors would like too point out, however, that glycosylated hemoglobin determination is useful in some cases such as chemical diabetes, diabetes in a remissive phase and diabetes in early infancy.
对39名糖尿病儿童和94名正常儿童测定了糖化血红蛋白水平。在部分糖尿病儿童和正常儿童中，还测定了HbA1c组分。在评估研究结果后，作者得出结论，出于实际目的，测定总糖化血红蛋白就足够了，并对该参数用于糖尿病儿童代谢平衡的常规监测的有用性表示怀疑。然而，作者也指出，糖化血红蛋白测定在某些情况下是有用的，如化学性糖尿病、缓解期糖尿病和婴儿早期糖尿病。
