一例在窦性心律下出现尖端扭转型室速现象的普尼拉明中毒病例？

Meanock C I, Noble M I

Postgrad Med J. 1981 Jun;57(668):381-4. doi: 10.1136/pgmj.57.668.381.

A case of torsade de pointes attributed to prenylamine is described. In addition, the authors show QRS axis variation of a similar nature in sinus rhythm. It is postulated that these changes of QRS axis direction, seen in ventricular tachycardia and sinus rhythm, are both manifestations of partial refractoriness, within the ventricle, producing gross changes in the mean QRS vector.

本文描述了一例由普尼拉明引起的尖端扭转型室速病例。此外，作者还展示了窦性心律时类似性质的QRS电轴变化。据推测，在室性心动过速和窦性心律中所见的QRS电轴方向的这些改变，都是心室内部分不应期的表现，会导致平均QRS向量发生显著变化。