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在普尼拉明治疗期间，注射碘他拉酸钠（康瑞420）诱发室性心动过速：一种可预测的药物不良反应相互作用。

Ventricular tachycardia precipitated by sodium iothalamate (Conray 420) injection during prenylamine treatment: a predictable adverse drug interaction.

作者信息

Duncan J S, Ramsay L E

出版信息

Postgrad Med J. 1985 May;61(715):415-7. doi: 10.1136/pgmj.61.715.415.

DOI:10.1136/pgmj.61.715.415
PMID:4022877
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2418259/
Abstract

A case of ventricular tachycardia occurring after intravenous injection of sodium iothalamate (Conray 420) into a patient taking prenylamine is described. Both of these drugs may cause prolongation of the corrected QT interval and the mechanisms of this potentially fatal drug interaction are discussed.

摘要

本文描述了一例在服用戊脉安的患者静脉注射碘他拉酸钠（康瑞420）后发生室性心动过速的病例。这两种药物都可能导致校正QT间期延长，并对这种潜在致命药物相互作用的机制进行了讨论。

相似文献

1
Ventricular tachycardia precipitated by sodium iothalamate (Conray 420) injection during prenylamine treatment: a predictable adverse drug interaction.在普尼拉明治疗期间，注射碘他拉酸钠（康瑞420）诱发室性心动过速：一种可预测的药物不良反应相互作用。
Postgrad Med J. 1985 May;61(715):415-7. doi: 10.1136/pgmj.61.715.415.
2
Prenylamine-induced ventricular tachycardia and syncope controlled by ventricular pacing.普尼拉明诱发的室性心动过速和晕厥可通过心室起搏控制。
Br Heart J. 1980 Sep;44(3):330-4. doi: 10.1136/hrt.44.3.330.
3
Prenylamine-induced ventricular arrhythmias and syncopal attacks with Q-T prolongation. Report of a case and comment on therapeutic use of lignocaine.
Cardiology. 1980;66(4):199-203. doi: 10.1159/000170867.
4
Possible female preponderance in prenylamine-induced 'torsade de pointes' tachycardia. Short communication.普尼拉明诱发的“尖端扭转型”心动过速可能在女性中更常见。简短通讯。
Cardiology. 1983;70(1):37-40. doi: 10.1159/000173567.
5
A case of prenylamine toxicity showing the torsade de pointes phenomenon in sinus rhythm?一例在窦性心律下出现尖端扭转型室速现象的普尼拉明中毒病例？
Postgrad Med J. 1981 Jun;57(668):381-4. doi: 10.1136/pgmj.57.668.381.
6
[Prolonged Q-T interval, syncope and prenylamine].[QT间期延长、晕厥与普尼拉明]
G Ital Cardiol. 1973;3(2):233-9.
7
[A case of prenylamine syncope (torsades de pointes)].
Kokyu To Junkan. 1985 Mar;33(3):453-8.
8
[Prolonged QT interval and "torsades de pointes" after therapy with prenylamin (Segontin) (author's transl)].
Schweiz Rundsch Med Prax. 1981 Apr 14;70(16):717-20.
9
[A case of the "long Q-T and peak-torsion syncope" syndrome caused by prenylamine].
Minerva Cardioangiol. 1978 Oct;26(10):687-92.
10
[Polymorphous ventricular tachycardia in patients receiving prenylamine].
Harefuah. 1979 Mar 1;96(5):227-9.

引用本文的文献

1
The prolonged QT interval--a frequently unrecognized abnormality.QT间期延长——一种常未被识别的异常情况。
Postgrad Med J. 1985 May;61(715):379-86. doi: 10.1136/pgmj.61.715.379.

本文引用的文献

1
Prenylamine-induced ventricular arrhythmias and syncopal attacks with Q-T prolongation. Report of a case and comment on therapeutic use of lignocaine.
Cardiology. 1980;66(4):199-203. doi: 10.1159/000170867.
2
A case of prenylamine toxicity showing the torsade de pointes phenomenon in sinus rhythm?一例在窦性心律下出现尖端扭转型室速现象的普尼拉明中毒病例？
Postgrad Med J. 1981 Jun;57(668):381-4. doi: 10.1136/pgmj.57.668.381.
3
Life-threatening ventricular arrhythmia.
Practitioner. 1981 Apr;225(1354):541-2.
4
The effect of prenylamine on the QT interval of the resting electrocardiogram in patients with angina pectoris.普尼拉明对心绞痛患者静息心电图QT间期的影响。
Postgrad Med J. 1980 Nov;56(661):753-6. doi: 10.1136/pgmj.56.661.753.
5
Cardiovascular radiology. Cardiac alterations during intravenous urography.心血管放射学。静脉尿路造影期间的心脏改变。
Invest Radiol. 1980 Nov-Dec;15(6 Suppl):S239-42. doi: 10.1097/00004424-198011001-00050.
6
Torsade de pointes due to prenylamine controlled by lignocaine.
Eur Heart J. 1982 Aug;3(4):389-92. doi: 10.1093/oxfordjournals.eurheartj.a061322.
7
Atrio-ventricular block after administration of lignocaine in patients treated with prenylamine.在用普尼拉明治疗的患者中，给予利多卡因后发生房室传导阻滞。
Postgrad Med J. 1982 Mar;58(677):175-7. doi: 10.1136/pgmj.58.677.175.
8
Alterations in heart rate and rhythm at urography with sodium diatrizoate.泛影酸钠尿路造影时心率和心律的改变。
Acta Radiol Diagn (Stockh). 1982;23(2):107-10. doi: 10.1177/028418518202300204.
9
Comparative evaluation of intravenous pyelographic contrast media and assessment of associated electrocardiographic alterations.静脉肾盂造影造影剂的对比评估及相关心电图改变的评估
J Urol. 1968 Feb;99(2):223-5. doi: 10.1016/S0022-5347(17)62678-8.
10
Electrocardiographic abnormalities associated with intravenous urography.与静脉尿路造影相关的心电图异常。
N Engl J Med. 1973 Jul 12;289(2):87-8. doi: 10.1056/NEJM197307122890209.