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[暴露于不同强度噪声下实验动物心肌中的酶变化]

[Enzyme changes in the myocardium of experimental animals exposed to noise of various intensities].

作者信息

Ivanovich E, Antov G

出版信息

Probl Khig. 1981;6:9-14.

PMID:7301807
Abstract

The activity of the enzymes: SDH,GIDH,LDH, GI-6-PDH, ATP-ase,PGM, G 6P-ase, PI, 6P-ase in myocardial tissue were studied under conditions of a 30-day experiment on albino rats, treated two hours daily, 5 days in the week, with noise with an intensity of 85 dB/A/ and 95 dB/A/. Under the effect of noise with intensity of 85 dB/A/ a tendency to inhibition of SDH and GIDH activity is observed, which after the treatment with 95 dB/A/ noise is statistically significant. With the latter noise level a significant enhancement of PI,6 P-ase activity is established as well as a tendency to enhancement of G6P-ase and ATP-ase activity. The data from the investigations carried out reveal the possibility of developing disturbances in the metabolism of myocardial tissue under noise effect.

摘要

在对白化大鼠进行的为期30天的实验条件下,研究了心肌组织中SDH、GIDH、LDH、GI - 6 - PDH、ATP酶、PGM、G - 6 - P酶、PI、6 - P酶的活性。实验中大鼠每周5天,每天接受2小时强度为85 dB/A和95 dB/A的噪声处理。在85 dB/A噪声的作用下,观察到SDH和GIDH活性有受到抑制的趋势,而在接受95 dB/A噪声处理后,这种抑制具有统计学意义。在95 dB/A的噪声水平下,PI、6 - P酶的活性显著增强,同时G6P酶和ATP酶的活性也有增强的趋势。所进行的研究数据揭示了在噪声影响下心肌组织代谢出现紊乱的可能性。

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