[Characterization of storage-induced release reductions in suppositories (author's transl)].

It is reported of the effect of storage at different temperatures on the release of aminophenazone, codeine phosphate, phenobarbital sodium and trapidil from suppositories, and of the physical parameter of the latter. Depending on the state of division of the drugs in the preparations and on the conditions of storage, drug release from suppositories was more or less affected, which alterations were but incompletely reflected in the physical parameters of the suppositories.