Rev Epidemiol Sante Publique. 1981;29(3):315-25.
The Swiss National Research Program on primary prevention of cardiovascular disease attempts to reduce major factors of risk and to evaluate the obtained effect. For this purpose two intervention towns and two control areas were selected according to quantitative and qualitative criteria. The samples were chosen in order to evaluate separately the global effect of the program, the effect of the baseline assessment and of the interventions addressed to individuals. The statistical advantages of the comparison of the same people at the beginning and at the end of the program are demonstrated. The discussion focuses on the benefits and on the drawbacks of a study without randomization for evaluating preventive actions aiming at the total community.
瑞士心血管疾病一级预防国家研究项目试图降低主要风险因素并评估所取得的效果。为此,根据定量和定性标准选择了两个干预城镇和两个对照区域。选择这些样本是为了分别评估该项目的总体效果、基线评估的效果以及针对个体的干预措施的效果。论证了在项目开始和结束时对同一人群进行比较的统计学优势。讨论集中在一项非随机研究在评估针对整个社区的预防行动时的优点和缺点。