Metzger U, Uhlschmid G, Largiadèr F
Schweiz Med Wochenschr. 1981 Sep 5;111(36):1303-6.
64 resections and 51 instances of cryosurgical treatment in 102 patients with pulmonary metastases are reported. Under clearly established conditions, parenchyma-saving resection is often the only curative treatment for pulmonary metastases. Survival rates are 72% after one year and 35% after 5 years. Resection is also indicated after a short interval between the treatment of the primary tumor and onset of lung secondaries. Prognostic factors are histology of the primary tumor and progress of pulmonary metastases, measurable by tumor doubling time and the onset of new secondaries during a given short time interval. Cryosurgery for multiple metastases or local inoperable tumor has a one-year survival rate of 48% and a 5-year survival rate of 26%. While systemic therapy will change the role of surgery, its importance will increase as a factor in combined treatment modalities.
报告了102例肺转移患者的64例切除术和51例冷冻治疗情况。在明确的条件下,保留实质的切除术往往是肺转移的唯一治愈性治疗方法。一年生存率为72%,五年生存率为35%。在原发性肿瘤治疗与肺转移灶出现之间间隔较短时,也应进行切除术。预后因素是原发性肿瘤的组织学类型和肺转移的进展情况,可通过肿瘤倍增时间和在给定短时间间隔内新转移灶的出现来衡量。对于多发转移或局部无法手术的肿瘤,冷冻治疗的一年生存率为48%,五年生存率为26%。虽然全身治疗将改变手术的作用,但作为综合治疗模式的一个因素,其重要性将增加。