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多发性内分泌缺陷综合征中的蝶鞍侵蚀与暂时性性腺功能减退

Sella turcica erosion and transient hypogonadism in the multiple endocrine deficiency syndrome.

作者信息

Gardner D F, Watlington C O

出版信息

South Med J. 1981 Nov;74(11):1415-7. doi: 10.1097/00007611-198111000-00033.

DOI:10.1097/00007611-198111000-00033
PMID:7302647
Abstract

A 42-year-old man presented with clinical and biochemical evidence of hypothyroidism, hypoadrenalism, and hypogonadism. Initial diagnostic studies suggested intrinsic pituitary disease and were supported by the finding of a roentgenographically abnormal sella turcica. Detailed endocrine evaluation subsequently showed normal pituitary function and primary target organ deficiencies. Adrenal and thyroid hormone replacement resulted in complete resolution of clinical symptoms and abnormalities of gonadal function. Thorough endocrine evaluation is needed in patients with multiple endocrine deficiencies.

摘要

一名42岁男性出现甲状腺功能减退、肾上腺功能减退和性腺功能减退的临床及生化证据。初步诊断研究提示存在垂体自身疾病,蝶鞍X线片异常的检查结果支持这一诊断。随后详细的内分泌评估显示垂体功能正常,主要是靶器官功能缺陷。肾上腺和甲状腺激素替代治疗使临床症状和性腺功能异常完全缓解。对于患有多种内分泌缺陷的患者,需要进行全面的内分泌评估。

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