Campbell B C, Elliott H L, Meredith P A
Toxicol Lett. 1981 Oct;9(2):121-4. doi: 10.1016/0378-4274(81)90027-8.
Blood and urine lead concentrations have been measured in 40 subjects with normal and impaired renal function. Derived renal lead clearance varied widely, but was not influenced by the degree of renal impairment. Lead, however, appeared to reduce its own clearance. These findings provide additional evidence of nephrotoxicity from sub-clinical lead exposure.
已对40名肾功能正常和受损的受试者测量了血液和尿液中的铅浓度。推导得出的肾脏铅清除率差异很大，但不受肾功能损害程度的影响。然而，铅似乎会降低其自身的清除率。这些发现为亚临床铅暴露导致肾毒性提供了更多证据。
