Distribution of 19-iodocholesterol-125I 3-acetate in the dog and the rat.

Since 19-iodocholesterol ethyl and methyl ethers and 3 beta-iodo-5-cholestene localized in dog adrenal, the distribution of 19-iodocholesterol 3-acetate was similarly studied. This ester was concentrated by the dog adrenal to the same extent as 19-iodocholesterol. Despite a previous report that the ester was not appreciably taken up by the rat adrenals, distribution experiments were undertaken, and the results showed that the ester preferentially localized in the adrenals of the rat as well as the dog.