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[孕激素治疗过程中子宫内膜腺棘皮癌的激素转化特征]

[Hormonal transformation characteristics of endometrial adenoacanthoma in the process of progestin treatment].

作者信息

Shenderëva T S, Shvedova L A

出版信息

Vopr Onkol. 1981;27(10):52-6.

PMID:7303557
Abstract

Changes in the histological structure of endometrial adenoacanthoma, as a result of treatment with 17 alpha-hydroxyprogesterone capronate, are discussed. The biopsy and resected material obtained from 11 patients was studied. It was shown that hormono-therapy results in an increased structural and functional differentiation of the glandular and squamous-cell components of tumor. Sensitivity to 17 alpha-hydroxyprogesterone capronate was established in 81.1% +/- 11.6 of patients.

摘要

本文讨论了己酸17α-羟孕酮治疗对子宫内膜腺棘皮瘤组织结构的影响。研究了11例患者的活检及切除组织。结果显示,激素治疗可使肿瘤的腺性及鳞状细胞成分在结构和功能上的分化增强。81.1%±11.6%的患者对己酸17α-羟孕酮敏感。

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