Müller G, Zimmermann G, Pimpl W
Wien Klin Wochenschr. 1981 Aug 7;93(15):479-84.
The success of selective proximal vagotomy in the treatment of chronic duodenal ulcer is dependent on complete denervation of the proximal part of the stomach, as well as on the preservation of antral innervation. Inadequate nerve dissection results in therapeutic failure. The most frequent cause of recurrent ulcers is incomplete vagal denervation of the acid-secreting cells. Therefore, it would seem desirable to use an intraoperative test to check completeness of vagotomy, giving the surgeon the possibility of rectifying an inadequate nerve section still at the time of operation. Among several methods the electrical stimulation test described by Burge and Vane has gained general acceptance. However, the question of whether the intraoperative test actually improves the results of vagotomy remains equivocal. In an initial series of 39 vagotomies we ensured completeness of denervation by the electrical stimulation test. In a subsequent series of 44 operations vagotomy was performed without the test. The patients were re-examined one and again two years following operation (clinical evaluation, gastroscopy and/or X-ray examination). The results of this retrospective analysis using the classification of Visick showed no difference between the two series. Hence, we have no reason to suppose that omission of the intraoperative test will result in an increased number of incomplete vagotomies, provided the surgeon has gained his experience in this operative procedure by using the test to check his surgical technique, which thereby becomes standardized. Thereafter, the Burge test becomes dispensible.
选择性近端迷走神经切断术治疗慢性十二指肠溃疡的成功取决于胃近端的完全去神经支配以及胃窦神经支配的保留。神经解剖不充分会导致治疗失败。复发性溃疡最常见的原因是泌酸细胞的迷走神经去神经支配不完全。因此,似乎需要使用术中测试来检查迷走神经切断术的完整性,使外科医生在手术时仍有可能纠正不充分的神经切断。在几种方法中,Burge和Vane描述的电刺激测试已被广泛接受。然而,术中测试是否真的能改善迷走神经切断术的效果仍不明确。在最初的39例迷走神经切断术中,我们通过电刺激测试确保去神经支配的完整性。在随后的44例手术中,未进行该测试。术后1年和2年对患者进行复查(临床评估、胃镜检查和/或X线检查)。使用Visick分类法进行的这项回顾性分析结果显示,两组之间没有差异。因此,我们没有理由认为,如果外科医生通过使用该测试来检查其手术技术从而使其标准化,进而在该手术操作中积累了经验,那么省略术中测试会导致不完全迷走神经切断术的数量增加。此后,Burge测试就变得不必要了。