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近端选择性迷走神经切断术前后术中电刺激迷走神经对氢离子分泌及血清胃泌素的刺激作用(作者译)

[Stimulation of H+ secretion and serum gastrin by intra-operative electrical vagal stimulation before and after proximal selective vagotomy (author's transl)].

作者信息

Schacht U, Fritsch W P, Rumpf P, Jacobs G, Hausamen T U

出版信息

Dtsch Med Wochenschr. 1977 Jun 17;102(24):894-6. doi: 10.1055/s-0028-1104984.

Abstract

H+ secretion and gastrin concentration were measured before and after electric vagal stimulation during proximal selective vagotomy in 29 patients with duodenal ulcers. Before vagotomy, H+ secretion and serum gastrin concentration significantly rose after stimulation, while after complete vagotomy H+ secretion remained below basal values, although serum gastrin concentration was significantly increased. These results indicate that without vagal innervation there is no gastrin secretion within physiological levels. The method is suitable for testing the completeness of the vagotomy, the results not agreeing with those obtained by pressure measurements (Burge's method).

摘要

在29例十二指肠溃疡患者进行近端选择性迷走神经切断术期间,测量了电刺激迷走神经前后的氢离子分泌和胃泌素浓度。迷走神经切断术前,刺激后氢离子分泌和血清胃泌素浓度显著升高,而完全迷走神经切断术后,尽管血清胃泌素浓度显著升高,但氢离子分泌仍低于基础值。这些结果表明,没有迷走神经支配,生理水平内就不会有胃泌素分泌。该方法适用于测试迷走神经切断术的完整性,结果与通过压力测量(伯奇方法)获得的结果不一致。

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