Danielczyk W
Wien Klin Wochenschr. 1981 Aug 7;93(15):500-1.
Pharmacotoxic psychoses resulting from therapy of advanced Parkinson's disease can occur in up to 60% of the patients. Treatment must not be completely discontinued in such cases. Clopenthixol (Sordinol, Ciatyl) in small dosage has been shown to be much more effective than all other types of therapy in the management of those psychoses. In a group of 28 patients treated with clopenthixol the progression of Parkinson's disease was not quicker than a control group of 30 patients not treated with clopenthixol. Both groups were of similar age and at a similar stage of the disease.
晚期帕金森病治疗引起的药物毒性精神病在多达60%的患者中可能出现。在这种情况下，治疗不能完全中断。小剂量的氯哌噻吨（索度罗、西阿替）在治疗这些精神病方面已被证明比所有其他类型的治疗方法有效得多。在一组接受氯哌噻吨治疗的28名患者中，帕金森病的进展并不比未接受氯哌噻吨治疗的30名患者组成的对照组更快。两组年龄相似，疾病阶段相似。
