Götz M, Popow C, Jarisch R
Wien Klin Wochenschr. 1981 Sep 4;93(16):514-6.
38 children with bronchial asthma were investigated for allergy (RAST), non-specific bronchial hyperreactivity (acetylcholine challenge) and reaction to physical exercise (free running and bicycle ergometry). 17 patients showed EIA caused by free running and 11 by cycloergometry. Patients with clear-cut allergy (n = 27, high RAST values, class 3 and 4) showed exercise-induced bronchoconstriction in a high percentage of cases (16 of 27 following running, 10 of 27 after bicycle ergometry). Such patients also had non-specific bronchial hyperreactivity. This would explain treatment failures after correctly performed specific immunotherapy.