Götz M, Popow C, Jarisch R
Wien Klin Wochenschr. 1981 Sep 4;93(16):514-6.
38 children with bronchial asthma were investigated for allergy (RAST), non-specific bronchial hyperreactivity (acetylcholine challenge) and reaction to physical exercise (free running and bicycle ergometry). 17 patients showed EIA caused by free running and 11 by cycloergometry. Patients with clear-cut allergy (n = 27, high RAST values, class 3 and 4) showed exercise-induced bronchoconstriction in a high percentage of cases (16 of 27 following running, 10 of 27 after bicycle ergometry). Such patients also had non-specific bronchial hyperreactivity. This would explain treatment failures after correctly performed specific immunotherapy.
对38例支气管哮喘患儿进行了过敏反应(放射性变应原吸附试验)、非特异性支气管高反应性(乙酰胆碱激发试验)和体育锻炼反应(自由跑步和自行车测力计试验)的调查。17例患者出现由自由跑步引起的运动诱发性哮喘,11例由自行车测力计试验引起。有明确过敏反应的患者(n = 27,放射性变应原吸附试验值高,3级和4级)在高比例病例中出现运动诱发的支气管收缩(跑步后27例中有16例,自行车测力计试验后27例中有10例)。这类患者也有非特异性支气管高反应性。这可以解释正确进行特异性免疫治疗后治疗失败的原因。