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[家兔自我刺激过程中背侧海马神经元的锋电位活动]

[Spike activity of dorsal hippocampus neurons of rabbits during self stimulation].

作者信息

Belyĭ V P

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1981 Jul-Aug;31(4):719-27.

PMID:7303895
Abstract

Responses of 47 neurones of the dorsal hippocampus were studied in a chronic experiment on free-behaving rabbits during self-stimulation behaviour. The achievement by the animals of the instrumental habit of pressing the lever produced stimulation of the lateral hippocampus. It was found that different hippocampal neurones change the frequency of their discharges at different stages of self-stimulation behaviour: some at the stage of the animal's approach to the lever, others during stimulation and still others in the poststimulation period. Inhibition and activation reactions in most of the neurones were of opposite direction at the moment of stimulation and in the poststimulation period. During the reinforcing stimulation the hippocampal theta-neurones were the most reactive.

摘要

在一项针对自由活动兔子的慢性实验中,研究了47个背侧海马神经元在自我刺激行为期间的反应。动物养成按压杠杆的工具性习惯会引发海马体外侧的刺激。结果发现,不同的海马神经元在自我刺激行为的不同阶段会改变其放电频率:一些在动物接近杠杆阶段,另一些在刺激期间,还有一些在刺激后阶段。大多数神经元在刺激时刻和刺激后阶段的抑制和激活反应方向相反。在强化刺激期间,海马θ神经元反应最为活跃。

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